Hi. Sorry to hear about your dog's cancer diagnosis. To answer your question about the mitoxantrone & piroxicam, when my scottie JJ had that treatment at CSU animal cancer center in 2008, it stopped the cancer from growing or spreading for 5 months. He had the chemo once every 3 weeks. No side effects other than some sleepiness the first night after each infusion. Then the tcc started growing again & they switched him to doxirubicin which made him sick so we didn't do that drug again & we went to just piroxicam. He went downhill quickly after that. One of the techs at CSU told me they had a female dog with tcc that had been doing mitoxantrone & piroxicam for two years & was doing fine. It depends on the dog--for some it doesn't help, for most I think it's like with my dog--it just stops it from growing for awhile. Then there are some that it really works great & they are given a lot of time by the mitoxantrone. My 11 yr old female scottie Scampi(daughter of the one I lost last year to tcc) now had been diagnosed with tcc & CSU is still recommending the mitoxantrone & piroxicam & they also have a new radiation treatment that targets only the tumor & they've had really good results with it. But the special radiation is pretty expensive. Hope this helps.
Joy