PSA drop after hormonal therapy

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PSA drop after hormonal therapy

by zofianir on Thu Mar 25, 2010 08:16 AM

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Have a prostate cancer

age 56
Gleason 7 (4+3)

PSA  before  hormonal therapy  18.11

After 30  days of hormonal therapy 

LUCIN 15.2

COSODEX 50mg

PSA drop  to 2.54

Is  that Normal ?

Thank You

RE: PSA drop after hormonal therapy

by skidan on Thu Mar 25, 2010 01:05 PM

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Yes its normal, what other treatment will you be using ? Hormonal therapy won't work forever and it is not a cure, plus who wants to live being chemically castrated. If you plan on only using hormonal therapy you need to change your diet and take supplements in order to beat the beast. Alternative treatment is what I have been using for 4 years and its been very effective.

Dan

RE: PSA drop after hormonal therapy

by Johnw100 on Thu Mar 25, 2010 01:16 PM

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It is hoped that PSA will eventually reduce to a  very low figure (eg under 1) after several months on Hormone Therapy, and  stay low for some time.

RE: PSA drop after hormonal therapy

by Johnt on Thu Mar 25, 2010 05:04 PM

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This is completely normal. psa should go down to undetectable in 3 months and if it stays there for 3 more months it is indicative that your PC is androgen dependent and HT should work for quite a while. You should also consider adding proscar as an additional blocker. If psa starts to rise within 3 months it idicates you have a large population of androgen independent cells and HT will not work long term and you will have to find another combination of drugs that does work. Only an experience oncologist should be treating you.

JohnT

JohnT

RE: PSA drop after hormonal therapy

by Badmamazoo on Mon Mar 29, 2010 11:00 AM

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Ray,

If you are on already on hormonal therapy, Proscar will not add any additional side-effects but it will take away the testosterone made outside of the testes. In other words,it provides for a total hormonal blockade. Dr Myers suggests staying on Proscar even after you come off Lupron for awhile. All of the hormonal blockades have nasty side-effects.

RE: PSA drop after hormonal therapy

by cccsu on Mon Mar 29, 2010 12:17 PM

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Will you/anybody lell what fruits are not good for PC and what are good?  Though my husband didn't confirm it but I want to know before hand.

RE: PSA drop after hormonal therapy

by cccsu on Mon Mar 29, 2010 11:59 PM

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I got it.  Thank you ricrossley.  My husband is going to see an urology tomorrow morning.  Hope it's negative.  All the best to you.

RE: PSA drop after hormonal therapy

by Graeme_UK on Fri Nov 12, 2010 10:04 AM

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Hello zofianir... Hi I would suggest, if you havent already done so you that you seek an opinion or second opinion to see if radiotherapy would be an option for you. In conjunction with hormone therapy the benefits appear to be very good. Im on an IMRT dose escalation trial in conjunction with zoladex. So far so good, after radiotherapy and 2 years into the 3 year trial. My initial psa was in the 40's and has been undetectable for more than a year. Whether that is due to the zoladex, radiotherapy or a combination of the two will not be known until I come of zoladex (assuming that my psa doesnt rise prior to coming off it).

I hope that you are coping. Best wishes.

RE: PSA drop after hormonal therapy

by Johnt on Wed Nov 17, 2010 04:38 PM

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For any Hormone Therapy your psa should drop to 0.05 and remain there for at least 3 months for the HT to be considered effective.

Instead of relying on undocumented internet information please read: "Beating Prostate Cancer: Hormone Therapy and Diet" by Dr Charles Snuffy Myers and "A Primer on Prostate Cancer" by Dr Stephen Strum to see what the two top experts in hormone therapy recommend and regular testing you should be undertaking like testestorone testing to see if the HT is doing what it is supposed to be doing.

JohnT

RE: PSA drop after hormonal therapy

by Blantyre on Tue Nov 23, 2010 12:34 AM

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Sounds good. Keep check with your Dr. Skip

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