Side Effects of Carac or Efudex

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RE: Side Effects of Carac

by AngieMN on Fri Apr 03, 2009 12:00 AM

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Good morning -

I am so happy I found this site and others who are going through this with me. I am 38 and have had Moh's surgery to remove BCC on my face. My derm suggested I use Carac as a follow up. I am to use for 2 weeks, once a day and then follow up with him. I have used for 6 days and have had no reaction what so ever. Can you tell me when most of you first started to see results? I have gone online and have seen pictures of what can happen and honestly, I am so scared!!

Thanks in advance for your info and support!

Angie

RE: Side Effects of Carac

by carrieann on Sun Apr 05, 2009 12:00 AM

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hi, Angie, Noranne, Eli and everyone!

How are you doing now?  For the lips, Eli, honey is very soothing. 

 Once you are able to drink out of a cup again, you may want to use glass rather than plastic when it is practical (like at home).  I don't know maybe just to avoid BPA chemicals, etc that may be an irritant to those tender lips.

My doctor told me not to use carac at the corners of my mouth.  I think because the skin sort of doubles up there, you get a lot of medication, and it becomes ultra sensitive.

Hang in there, everybody! 

RE: Side Effects of Carac

by noranne on Sun Apr 05, 2009 12:00 AM

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Hi Everyone,

Thanks for your post, Carrieann.  Angie - I really did not react to the Carac until about two weeks into the treatment.  Once the reaction started, I got very red, irritated and uncomfortable.  I took a benadryl at night on the worst days and it helped me sleep.  This message board was of great help since I had the input from others at various treatment stages.  For myself, I felt like the medication got into my system and I felt lousy.  About two weeks after treatment was over, I felt like myself again.

Exercise helped - I fast walk several mornings a week very early am at a local college track.  Getting out in the fresh air was tonic for me and the cool air felt soothing on my skin.  

Cover up wise I did very well with the help of some mineral makeup.  I found a green tinted primer that neutralized a lot of the redness, then covered it carefully with a mineral concealer.  I had no ill effects from using the mineral makeup and my doctor couldn't believe it when I took the makeup off in her office and she evaluated my Carac progress.  I worked throughout the treatment and although I had some very tough days, I was able to still go out in public without too much of a problem.

Each day of treatment is a day closer to the finish line.  I'm very glad I did it now and yes, I would do it again if I was advised to do so.  It is worth the effort to hopefully avoid more serious issues down the roard.  The bonus is that my skin looks the best it has in years!

Hang in there and share the support.  There are so many wonderful people on this board.  I can't thank Mom2three and Irishgirl enough - they were there throughout my treatment and if I can pass along any of that positive energy to someone going through this, count me in.

 

RE: Side Effects of Carac

by Eli14 on Tue Apr 07, 2009 12:00 AM

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Hello to Everyone and Carrie Ann

So here I am on day 15 of Carac "attack" on my lips...2 weeks to go unless my derm. tells me otherwise when I see him.The corners of the mouth are getting so "crusty" and "pussy/bleedy" at times it hurts to put the cream on it, a burning feeling, but gotta do it. The upper lip has formed a dark red line and has a burning feeling as well. The lips themselves have been chapped and peeling a white/yellow skin that sometimes "hangs" and is still attached, not pretty to the eye...It is exactly as you guys say it, day 14-15 it feels that the cream is starting to really do what it's supposed to do, so for those who wondered at day 6, 7, 8 if the cream is a bad batch or maybe does not work on them, do not worry, be patient, it will start to act really soon. One thing about putting it on my lips is that it has made me sneeze very often and I do feel more tired than usual...it might have a draining effect on our metabloism, but I am not sure.

Let's see what the derm says at the appointment, and good luck to all of us who are going through this. Honestly, if you can, take a picture every week as you will see the stages of the treatment better.

Eli

RE: Side Effects of Carac

by The_Snowman on Tue Apr 07, 2009 12:00 AM

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Hey Folks,

Just popped in to say hello to mom2three and everyone else that was around a few months ago (kind of a "class reunion" thing that we had talked about).

I dropped the ball a bit and let April sneek up without realizing it.  I haven't had a chance to read through the posts yet, but I hope everyone's doing well.  I should have some time to catch up over the next day or two, so I look forward to reading up on how everyone is recovering.

I'll check back in when I get myself back up to speed reading through this thread.  Until then, good luck to all.

The Snowman

 

RE: Side Effects of Carac

by AngieMN on Wed Apr 08, 2009 12:00 AM

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On 4/5/2009 noranne wrote:

Hi Everyone,

Thanks for your post, Carrieann.  Angie - I really did not react to the Carac until about two weeks into the treatment.  Once the reaction started, I got very red, irritated and uncomfortable.  I took a benadryl at night on the worst days and it helped me sleep.  This message board was of great help since I had the input from others at various treatment stages.  For myself, I felt like the medication got into my system and I felt lousy.  About two weeks after treatment was over, I felt like myself again.

Exercise helped - I fast walk several mornings a week very early am at a local college track.  Getting out in the fresh air was tonic for me and the cool air felt soothing on my skin.  

Cover up wise I did very well with the help of some mineral makeup.  I found a green tinted primer that neutralized a lot of the redness, then covered it carefully with a mineral concealer.  I had no ill effects from using the mineral makeup and my doctor couldn't believe it when I took the makeup off in her office and she evaluated my Carac progress.  I worked throughout the treatment and although I had some very tough days, I was able to still go out in public without too much of a problem.

Each day of treatment is a day closer to the finish line.  I'm very glad I did it now and yes, I would do it again if I was advised to do so.  It is worth the effort to hopefully avoid more serious issues down the roard.  The bonus is that my skin looks the best it has in years!

Hang in there and share the support.  There are so many wonderful people on this board.  I can't thank Mom2three and Irishgirl enough - they were there throughout my treatment and if I can pass along any of that positive energy to someone going through this, count me in.

 


 

Hi Noranne  (and others)

Thank you for responding to my message. I really appreciate it! I guess when the medicine starts to react, I'll know what to expect. Last night was day 11 for me and I still don't have any reaction. I go to see my derm on Monday (5 more days) and I am confidant he will advise me to continue using another 2 weeks or so. From what I've read, those will be the weeks that things heat up. It is so interesting that everybody has such different reactions to this med. Are there different doses, perhaps I'm on a lower dose? How much cream do you all use? I am treating my entire face and the derm said just a pea size amount should do it...maybe slightly more? The only reaction I may be having is there have been days I feel a bit nauseated and I've wondered if it could be the meds?

Again - thank you for responding - I like feeling prepared for what I will be going through in the next few weeks. I guess no matter how bad it gets, its better than having Moh's surgery again....and it sounds like my skin will look great when this is through.

 Angie

RE: starting with carac

by Gambit on Wed Apr 08, 2009 12:00 AM

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On 5/22/2008 Dorothy11 wrote:

I just got told that I have 6 precancerous spots on my face. So I feel fortunate to have found this message board. I brought the Carac cream home today and have real concern about starting. 1) effects of the warm weather 2) unanswered questions: will there be scarring after; will it cause hair loss; the 'look' of redness. 2) I was told to use every other day for 6 weeks. I probably am going to call the MD before I start. After reading on the internet, I am aware that the DERM MD told me nothing, except that my face will get red. So I look forward to the support from this site.

 

Carac

by beitzen88 on Tue Apr 14, 2009 12:00 AM

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New to forum. Interesting. I have had 10 or 11 MOHS surgeries alone and also used carac 4 or 5 times over large areas. Each time you use it on the same area it is easier. Much easier. In other words, you should use this treatment for the rest of your life on a sked you discuss with your doctor. I do it once a year, however, the number of days you use it will/could vary.

10 or 11 MOHS is not by any means a lot in the world of skin cancer.

I just want to say that you must remember to get after all the parts of your body exposed to sun--not just one area. If your forehead is in bad shape, I do not think the rest of the face, ears, neck, chest, arms, shins had any less exposure.

I have used it on all those areas. The first time I used it on my arms, dozens and dozens of scabs formed. The fourth time I used it on my arms, almost nothing. I could put carac on  for 8 wks now and I bet it would only get a little red. Similar with my face but the face is more sensitive than the arms of course. I also push the creme about a inch up into the hairline. You will be surprised.

Do not forget the shins. That is a bad place for skin cancer. I was raised in Hawaii and California, sailed across the Pacific a few times, so had lots of sun damage.

 It is my opinion that while carac does a good job of getting pre cancer cells and maybe a few superficial basils, it does not get existing cancer so do not be lulled into any sense that this is it. You need to go in twice a year, get an aggressive dermy to do the biopsies--based on my long history, I go in every 3 months. I do not care what it costs, it is less than MOHS and plastic reconstructive surgery. I should know.

A quick check of past posts reflected headaches, etc. I had this reaction also. Normal I think. Also felt tired but who knows why. The issue of scars, especially on the cheekbones will scare you a bit. I had pretty deep scars when the scabs fell off. The scars went away after 6 months. No big deal. I did not think they would go away or the brown spots, but they did and my face looks a lot better.

My main point is not carac per se, but if you are using this, your doctor had a reason to put you on it. Do not think your skin cancer is gone, skin cancers can be well under the skin anyway and pop to the surface years later, which is why MOHS helps to trace the track of these cancers. Be aggressive, see your doctor at least twice a year, get the biopsies and not hope they are nothing. Carac I think is a good step, but it will not make up for existing problems that may be there. You just can't get rid of skin cancer like that. I wish it was that easy and believe me, I really burned my ears off with carac and it did not do anything for existing cancer and I lost the top ridge of my ear. Carac just can't burn down enough to get all of the cancer out of there. Impossible. It can keep many pre cancers from becoming cancer and wish I had this creme many years ago. Might have saved me a lot of trouble.

Stay on top of this and do not think for a moment that skin cancer is not a tricky devil, it is. Carac is part of the solution, but only part. A well thought out program of screening with your doctor is the other part, finding a good MOHS surgeon that you are comfortable with, discuss what the possible outcomes of MOHS surgery might be and how you are going to deal with it. Remember, MOHS is only for the face, not the rest of the body like chest, arms, legs, etc. and there is no way any doctor can tell you how many slices he/she is going to take off since they just will not know until they start the pathology of the removed tissue.

Hope this helped in some small way to help others not make the mistakes I made over my life with my skin--if it scared anyone, well, better to find out now. This is why I do not care at all what I look like during the carac process--I am long past that and just glad it is available. I also do not care about itching, pain, etc. Small price to pay and once you do it, the next time around will be no big deal.

For general information, I have used carac for as little as 10 days and as much as 4 weeks. Depends on the reaction and the advice of your doctor. I have also found every doctor has a different way of using carac and I think that variance has to do with your history and the results of other patients that your particular doctor has studied.  No two dermatogists have told me the same thing and since I move around a lot due to work, I have seen a few. I do modify what they say with what has worked for me in the past which is a minimum of 2 weeks, better to go longer probably if you can do it. If you can't make it past 3 weeks, I think go in and see the doctor and try again in 6 months or so. It does get much easier with future applications. Nothing to be worried about but stay in contact with your doctor.

Last thing, I take photos of my reactions, download them onto photopaper and take them in. Often, the big scabs have fallen off and started to heal. I like to show the doctor the bad areas so he can really check that out in case there is a possiblility of a biospsy required for that area. Does not hurt to document what is going on and share that with the doctor. The doctor will appreciate it and it helps in the planning of your situation.

 

 

 

 

 

RE: Carac

by beitzen88 on Tue Apr 14, 2009 12:00 AM

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On 4/14/2009 beitzen88 wrote:

You just can't get rid of skin cancer like that. I wish it was that easy and believe me, I really burned my ears off with carac and it did not do anything for existing cancer and I lost the top ridge of my ear. Carac just can't burn down enough to get all of the cancer out of there. Impossible. 

I want to explain the carac did not cause me to lose the top part of my ear, that area was surgically removed during MOHS later.

RE: Side Effects of Carac

by Irishgirl on Tue Apr 14, 2009 12:00 AM

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Hi Everyone-Noranne,

Noranne, glad to hear you are doing well! I am now 2 months post treatment. Hard to believe it has been that long. My face looks great and it is absolutely worth the pain. I am a sunscreen nut now.

Like Noranne, I felt nauseous when I was being treated, I had a lot of difficulty sleeping as well. But just hang in there it is relatively a short period of time (although it may not seem like it now). It will be worth it in the end, not only for your health, but you will look fantastic. I did not have any scarring, my skin is smoother than it has been in many years.

Hang in there, this too shall pass!!

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