Has your wife's doctor done a biopsy to determine if it is a lymphoma? She should also have a catscan. If he assumes and does't run tests to be certain what it is, then tell him you would prefer to have tests done to be safe. I was told over and over for three months I had pnuemonia and they were wrong!Lymphoma is highly curable these days.Symtoms can include, weight lose, night sweats,a knot that doesn't go away,weakness,loss of appetite.If you feel you need a second oppinion then by all means get one, thats a patients right.Please keep me posted on what your wife finds out.