"without clinical trials, Salvestrols have no validity"
Respectfully, this is the type of thinking that often leads to a person's demise, when dealing with C
There are many things that have great validity, that haven't undergone clinical trial
Gerson therapy is a prime example. High Dose vitamin D is another (look to the work of Dr Joe Prendergast, Stanford Univ )
Once you understand Biochemistry, you'll understand the 'Validity' of these so called 'unproven' therapies