Chemo Leaking Port

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Chemo Leaking Port

by Nastro on Thu Jul 06, 2006 12:00 AM

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Has anyone had any experience w/a port that has had a leak and leaked the chemo out into the soft tissue? It has apparently been leaking for the past 2 treatments. My sister has colon cancer and taking Panitumumab-trial drug, Avastin, five FU, oxyplatnin, and one other cancer drug. The nurse said she "didn't think it would cause any damage". Surely that has happened to someone before and they have some idea of the consequences.

Chemo Leak

by Embee on Fri Jul 07, 2006 12:00 AM

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don't know specifics re admin of chemo in your sister's case - but my (late) wife experienced severe chemo burns during an isolated limb perfusion procedure as the result of apparent chemo leakage. (Procedure uses high concentrations and somewhat elevated temps). Upshot was 3 mos hospital stay to treat and stabilize burn and resulting infections, plus months of daily home care to tend to the damage. (Medium in question was Melphalan). m. bieman

Chemo Leakage

by Nastro on Sat Jul 08, 2006 12:00 AM

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What is a limb profusion and was the leakage from the port? She is having swelling and pain in her neck, basically all around. She has colon cancer stage IV. She has been taking a trial drug, panitumumab although I think this is mostly chemo that has leaked into the soft tissue.


by Embee on Sat Jul 08, 2006 12:00 AM

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For a very condensed description of ILP ,Google 'isolated limb perfusion + harvard'. Leakage in our particular case was into/onto soft tissue - but the media would likely have been more aggressive than in your sister's situation because of greater concentration, plus temp. Would still ask questions.

Port Leakage

by Nastro on Thu Jul 13, 2006 12:00 AM

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Did the actual leakage cause any problems in the soft tissue? She has had another port put in and haven't mentioned doing an isolated limb perfusion. Just wondering what the chemo in the tissue can cause.
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