Cancer progression viz PSA levels

3 Posts | Page(s): 1 

Cancer progression viz PSA levels

by Viking on Fri Jun 03, 2011 10:28 AM

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I had RP in Jan 2007. At that time my PSA was 17. Prior to the RP I had treatment for 6 months which shrunk my prostate size from 72mg to 50mg and reduced my PSA to 0.04.

By September 2009 my PSA had climbed to 0.26. I was given a six month course of hormone deprivation therapy and in April 2010 underwent radiation salvage treatment. In May 2010 my PSA was 0.04 and in November 0.26 again. My current PSA (end of May 2011) has doubled to 0.60.

My question is that progression rate is determined to be agressive when there is a fast doubling time. In my case my PSA has doubled in 6 months. However is doubling when the PSA level is less than 1.0 really considered to be doubling. Or can I take comfort in the fact that it is still only 0.60 four and a half years after my RP.

I guess what I am asking is the fact that my PSA has doubled in the past six months an indicator that things are going downhill rapidly?

Please don't reply if you just want to peddle me some magic drug, I am tired of replies like this.

RE: Cancer progression viz PSA levels

by skidan on Sat Jun 04, 2011 01:16 PM

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On Jun 03, 2011 10:28 AM Viking wrote:

I had RP in Jan 2007. At that time my PSA was 17. Prior to the RP I had treatment for 6 months which shrunk my prostate size from 72mg to 50mg and reduced my PSA to 0.04.

By September 2009 my PSA had climbed to 0.26. I was given a six month course of hormone deprivation therapy and in April 2010 underwent radiation salvage treatment. In May 2010 my PSA was 0.04 and in November 0.26 again. My current PSA (end of May 2011) has doubled to 0.60.

My question is that progression rate is determined to be agressive when there is a fast doubling time. In my case my PSA has doubled in 6 months. However is doubling when the PSA level is less than 1.0 really considered to be doubling. Or can I take comfort in the fact that it is still only 0.60 four and a half years after my RP.

I guess what I am asking is the fact that my PSA has doubled in the past six months an indicator that things are going downhill rapidly?

Please don't reply if you just want to peddle me some magic drug, I am tired of replies like this.

Viking

 A psa that is doubling every six months is not good. It really doesn't matter if it is less than 1.0, it is all about velocity.  As long as your psa continues to double every six months it is growing at a good rate.  You need to do something about it. My velocity was much worse after treatment, however you are not interested in what I did, you should talk to your doctor.

Dan

RE: Cancer progression viz PSA levels

by POOKIETRAIN on Sun Jun 05, 2011 09:43 PM

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I believe the doubling rate and velocity is significant even though it is below 1.0. You may find out

 that it will start to take off more aggressively as time goes on. PSA should always be 0 or undetectable after RP. I know since I have had the same experience. Scary, but do something ASAP.

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