Categorizing tumors by cell type and not the organ they grow in may alter treatment, experts say
by MickSiagian on Wed Sep 14, 2011 07:09 AM
Hi all, I am in Indonesia. We really need advice for my wife treatment. My wife is 44 years old. Family history from her no one have a cancer. My wife has had 2 times operation for her breast. Firstly Doctor has been made Excision operation for about 12X8 mm size of the tissues. Then the biopsy result was Medullary Carcinoma Mammae. By its Biopsy result has been made for the second operation about 3 cm around of the first operation and taken 15 pcs lymph node. From the biopsy and IHC Clear and clean from the tumor and malignancies and outwarding appearance of P63 gave positive reactions in the immune cells in the ductuli mioepitel no need to continue for treatment. But the results of the first excision biopsy operation concluded Medullary Carcinoma mammae. It has been requested again to IHC for the final decision and the result is Estrogen and progesterone Receptor Negative, and c-erb B2 positive. Doctors Oncologists finally make a letter to Dr. Radiation Oncologist to do 30 times the radiation. And then later on chemotherapy. He said although there was no malignancy of the tumor at the surgery BCS, as it is standard procedure. I think it's very painful. As Doctor said Medullary is less aggressive compare to others type of carsinoma and good prognosis, So, Does she still need to radiation and chemotherapy? Thank you for your kindness to us. A restless husband
by MickSiagian on Thu Sep 15, 2011 02:18 PM
I really need an opinion and suggestion from all of you.
by kayatlanta on Thu Sep 15, 2011 10:08 PM
I did not need any radiation and chemo but two of my friends did and despite their treatment they died. The message, breast cancer is a dangerous disease that cannot be taken lightly. It sounds like you don't trust your doctors, so maybe a second opinion is in order. Your doctors made their recommendations based upon the results of all types, and amounts sands of women with all kinds of cancer. I learned all about chemo because I was in a good job but uninsured so I was expecting to spend thousands of dollars for chemo. Imagine my shock when they said I didn't need chemo. If they had recommended chemo I was prepared to get a second mortgage on my home to pay for the chemo.
by MickSiagian on Fri Sep 16, 2011 08:14 AM
Hi, What is the reason that Oncologist asked not to give a radiaton eventhought Chemo. Is it because pathology report came no malignancies? You are a very lucky and happy people about it. But if you can tell me more detail history about. Warm Regards,
by kayatlanta on Fri Sep 16, 2011 12:55 PM
Even though the surrounding tissue was cancer free,she still has breast cancer. Cancer cells could have gotten into her body. You don't want to forgo chemo and radiation and then ten years from now she gets metastises in her lungs, bones, or brain. Herp positive means she needs chemo. Be thankful she is herp positive because tripple negative neg est, proges, and herp is a deadly combination which is what my friend had. You can wait years until the cancer comes back and then treat it but I would not recommend that. Why one doctor recommended no radiation and another doctor recommended to have radiation- different oppinions on a very complex subject. Is a second oppinion possible?
by MickSiagian on Wed Sep 21, 2011 02:57 PM
Thanks for your replied. One thing still a question in my mind, if no more identified on tissues margin 3 cm far from first excition and lymp node of tumor or malignancies, does it still need tratment or it is only pretending to make sure? So if it gives all things type of treathment already, is there assuring no more metastises in the future?
by kayatlanta on Wed Sep 21, 2011 05:49 PM
As I said before, there is no way to be 100% sure there will be no metastases but following the treatment regime the oncologist and radiation specialist recommend is the best way to get the highest percentage of not having metastases.
Clear margins and negative lymph nodes are very good signs but it is most important that your wife follows the MD's treatment recommendations even if they order more chemo or more radiation. Ask them to explain.
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