Phase II Trial GDC-0980

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derrygrath

Is anyone going on this trial?

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myboys2

Not us just read about it interesting keep me posted!!

Gail mother of Cody 21

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derrygrath

My husband just started today. First scan in 8 weeks.

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Bethan

Are you in the US I'm hoping that this trial will come to the UK

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Bethan

Sorry I've just realised that this a trial my husband may be doing. I mistook it for another trial which I think is only in the us at present. will be very interested to see how it goes

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Bethan

Still trying to decide on whether to go on this trial.Any thought anybody?

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derrygrath

My husband has been on this trial since Tuesday. He was randomized to receive GDC-0980. So far he has no side effects. We won't know if it working until the scan in 8 weeks. It is the only trial that he was eligible for. It is better than the alternative.

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derrygrath

My husband has been on this trial for 11 days now. A few days ago I could sense that something was not right with him and I tested his blood sugar. It was 400. After seeing an endocrinologist, he is now on 2 oral meds for diabetes. He will continue to test blood sugar 3x a day and adjust meds as needed. He is continuing on the trial. High blood sugar is a side effect of M-tor drugs. His blood sugar was normal before he started the GDC.

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derrygrath

My husband is now 2 weeks into the trial of GDC-0980 and now has to take 2000mg a day of Metformin, 8mg a day of Glimeperide and now starting today injecting himself with insulin just to control his blood sugar which is raised as a side effect of the drug. 6 weeks to go for the CT scan and the tumors that we can feel under his skin are not any smaller.

Has anyone tried this drug yet or has anyone gotten diabetes from Affinitor?

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Bethan