One patient with glioblastoma still alive nine years later
by Cristiana on Mon Mar 19, 2012 06:47 AM
I was wondering , besides MGMT methylation , if left side tumor or right side one is any prediction for long time survival ??
by siblingof on Mon Mar 19, 2012 12:06 PM
by jon4156 on Mon Mar 19, 2012 02:09 PM
I've never seen any statistics that have been kept for tumor location as it relates to overall survival and I suspect that with everything considered, excepting inoperable tumors, placement likely doesn't matter. The key factors for long term suvival are age, general health, good surgical results, and good toleration of post-surgical therapy. All generalities in a world of individual specifics which makes speculating whom is going to be a long term survivor rather difficult.
Without intending to trivialize brain surgery, removing a tumor is probably the most predictable part of the equation. Total resection is likely to produce a better outcome than 50% resection if everything else about the patients are equal. One of the hurdles with surgery is that tumor placement does affect overall post-surgical outcome. If the tumor is located near the speach or motor skills area of the brain than the likelyhood of having post-surgical issues is much higher which can ultimately affect overall survival.
So you could likely make some very general conclusions regarding tumor placement and overall survival but because there are so many individual particulars involved I'm not sure those conclusions would be very valuable in most cases.
by Cristiana on Mon Mar 19, 2012 03:05 PM
by huxley2006 on Tue Mar 20, 2012 04:46 PM
The only thing I would add is that in my case the tumor was in such a "good "location I have been able to go through multiple aggressive surgeries without suffering any cognitive impairment. Think location does play a role in LTS but as to where I think the best statement would be "not near any vital areas of the brain and amendable to multiple resection".
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