Though guidelines suggest screening starts at 50, researcher says it's premature to change them
by lk1965 on Fri Mar 23, 2012 02:17 AM
Just heard on FOX news about this PEGPH20 enzyme that studies have shown to improve delivery of chemo drugs into pancreatic tumors by expanding blood vessels. I Googled it, and the information out there looks very promising. It is currently in phases 1B & 2 trials right now in Seattle, WA and New Hyde Park, NY. Was wondering if by any chance, anyone here on this forum is (or has a loved one) currently particpating in this trial?
by lk1965 on Fri Mar 23, 2012 02:20 AM
Here is a news link on it:
You'll have to copy & paste it, as I can't figure out how to do a hyperlink.
by lk1965 on Fri Mar 23, 2012 02:24 AM
Another good article on it:
by lk1965 on Fri Mar 23, 2012 02:26 AM
Sorry about that...posted the same article twice! Here is the correct one:
by shirleyfromMI on Fri Mar 23, 2012 04:43 PM
Awesome,This sounds so promising, and like they said I hope this is the "game changer" for Pancan. I'm so hopefull reading this new info on this drug. God please let this be the "Game changer" Soooo many are looking for. Thanks for posting it made my day to read.
by kperman on Mon Jan 11, 2016 05:26 AM
I know this is from a few years ago, but I know someone who has just started this clinical drug trial of the PEG last week for Pancreatic Cancer. The side effects are pretty unbearable so I am wondering if anyone here knows of anyone who personally used this drug, and their experiences and survival rates.
I'm afraid she's not wanting to continue with the drug b/c of the side affects, she may just stick to chemo.
by Matty11 on Tue Jan 12, 2016 09:02 AM
MY wife is currently on the peg trial. She started in August and is now in week 24. Her side effects have been minimal and through the first 16 weeks her scans have shown marked shrinkage and overall decrease in number of tumors.
I will add that she is only 41 so her age Is likely a large factor in her tolerance of trestment.
She has her 3rd scan done tomorrow so the hope is further progress.
My best to everyone dealing with this awful disease!
by kperman on Thu Jan 14, 2016 05:18 AM
Wow, that is great news! How did the 3rd scan come out? My best wishes for you and your wife, she is way too young to have to deal with this.
If you or your wife is up for it, I would love to chat with her or email with her regarding the PEG trial. It's my mom (age 70) who is currently going through this right now and she is the only one that her dr is working with at the moment in the trial. She is having terrible cramping in her feet especially as well as all over her body. I know you said your wife had minimal side effects but I'm wondering if she ever experienced these intense cramps. We're trying to manage with medication, but it's not really helping.
I just think it would be helpful to communicate with someone that is going thru something similar and on the same trial, sometimes makes you feel better. If the side effects continue so badly, she will not want to stay in the trial and the trial is our one big hope.
You can private message me if you like. LMK if this is something she would be OK with. Thanks in advance!
by Matty11 on Wed Jan 20, 2016 08:17 PM
I thought I had responded to this but I guess it didn't go through.
Her third scan was reviewed yesterday and the tx continues to show marked improvement in size and overall number of tumors.
I asked her about cramping and she did have some but nothing too debilitating. I think her age has helped her tolerate the tx quite well.
I think it's really a personal decision on whether it's worth the side effects of a trial and chemo. Each case is different. I'm sure my wife would be open to some form of communucation, not sure what makes sense. Maybe email?
Hope things have gottenbetter!
by nov94 on Thu Jan 21, 2016 06:19 PM
Thanks to you all for sharing your info.
Can you please post a link to the trial you are talking about?
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