Clinical Trial - Sugen

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Clinical Trial - Sugen

by Shari_W on Tue Jul 15, 2003 12:00 AM

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My sister was told back in March that she had Neuroendocrine Cancer - Liver Metastasis Cancer. In May they did Chemoembolization on one side of her liver, about two or three weeks after this treatment she called her at home and told her she had a tumor in the bone in the sinus area. She is very weak and has no appetite. They told her about a new experimental drug called Sugen that some people have had positive results with, my sister is thinking about trying this drug. Has anyone else heard of this program or has anyone participate in this trial? They type of tumors she has are carcinoid. Any info would be very helpful. Shari

Clinical Trial - Sugen

by Patrick_H on Thu Aug 05, 2004 12:00 AM

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Shari, I am very sorry to here about your mother's condition. I hope tha she can find the help sh needs to get better. Sugen is actually a California-based company that wa acquire by Pharmacia. Pharmacia, and some of Sugen's leading candidates have since been acquired by Pfizer, Inc. Sugen's research ws primarily focusedon developing antiangiogenesis comounds - compounds which help prevent a cancer from forming its own blood supply around a tumor site. The cndidate would probably had a number associated with it, such as SU101. This would have identified the specific compound. Best wishes and good luck, Regards, RP

Sugen Drug

by Sherryc on Wed Aug 24, 2005 12:00 AM

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Shari, I am so sorry for your sister's misfortune. My husband has renal cell carcinoma that, like your sister, has metastasized to his lungs, bone, and spots on his liver. He is currently qualifying for a clinical trial on the sugen drug. The word on the street is that it is having amazing results of not only shrinking the tumors, but, in a few cases, making them disappear completely. The hazard is that it is very very hard on the heart. Some trials require a muga scan on the heart, which measures the ejection output on the left ventrical. 50%., or .5 is normal, and helps in qualifying for the trial, depending on which one you are trying to get into. Lower than that can be grounds for disqualification. Some trials do not require that test, and you can get in on a contingency basis, again, depending on where you are, and how "healthy" your sister is. Good luck to you both. Sherry, Los Gatos, CA
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