Seizures after 2nd GBM surgery

My husband started having seizures about a week after having a 2nd crainiotomy.  He was on 1000mg of Keppra a day (preventative) when they started.  He was combative and confused, but his sodium levels were a little low so they blamed it on that.  A few days ago, he started having tremors and staring off into space and it became obvious he was having seizures.  They upped the Keppra, but he still has eye blinking and a twitch in his cheek.  It reminds me of tourrettes syndrome.  Does anyone have any experience with anything like this?  He is so exhausted.  He sleeps most of the time. What drugs have worked for you?  He was on Dilantin after the last surgery and had no problems, of course he might not have had any seizures then.

My wife was diagnosed in Oct '11 and had surgery in Nov.  In late December she had multiple seizures and required 4 weeks in the hospital, two of those in an induced coma until they could get the seizures under control.

She is currently on 240mg of phenobarbital and 7.5 mg of diazepam to keep her seizures at bay.    She only recently started the diazepam as she was having several petit-mal seizures a day.  She was previously on Keppra but I don't recall the dosage.  She also takes 40 mg of hydrocortisone daily. 

She just completed the 3rd round of 5/23 390mg Temodar and needs to reduce the dosage due to a low platelet count.  Her next MRI is coming up on Aug 2nd.  

I sure hope it's low sodium- I'm on 3000 units of Keppra and 1800 Tripletal and was still having seizures. Up until 3 wks ago when I took my 1st Avastin treatment. Wishing you and your husband the best. I know when I started having seizures it was growing so be prepared for that:( Ellen

For my husband, decadron seemed to help with the swelling after surgery.  He would have facial twitching.  He couldn't take Dilantin because it gave him a bad rash.  Hopefully your neuro oncologist can find an answer for you?  Swelling also can contribute to fatigue, which is what John is combating right now.  God Bless.

My mom had her 2nd surgery last Wed and today she had a seizure at hospital.  Dr. said it could be for many reasons.  Hopfully she will be home tomorrow.