thapsigargin phase 1 trials for PC cure

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thapsigargin phase 1 trials for PC cure

by Viking on Thu Jul 12, 2012 06:58 AM

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I cannot find reference on CC to this article in the 'New Scientist'. It looks quite promising but then again it is only on phase 1 trials. You will see from the article that the research has been on going for some 15 years so hopefully it may hold out some hope of a PC cure rather than a slowing down. Check out the article in 'New Scientist' and ask your Oncologist/Urologist about it. The more people who show interest the quicker things might move.

http://www.newscientist.com/article/dn21983-death-carrot-cou

Viking

RE: thapsigargin phase 1 trials for PC cure

by rjcrossley on Thu Jul 12, 2012 11:44 AM

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On Jul 12, 2012 6:58 AM Viking wrote:

I cannot find reference on CC to this article in the 'New Scientist'. It looks quite promising but then again it is only on phase 1 trials. You will see from the article that the research has been on going for some 15 years so hopefully it may hold out some hope of a PC cure rather than a slowing down. Check out the article in 'New Scientist' and ask your Oncologist/Urologist about it. The more people who show interest the quicker things might move.

http://www.newscientist.com/article/dn21983-death-carrot-cou ld-hold-the-key-to-new-cancer-drugs.html"" target="_blank" rel="nofollow">http://www.newscientist.com/article/dn21983-death-carrot-cou target="_blank" rel="nofollow">http://www.newscientist.com/article/dn21983-death-carrot-cou

Viking

Hi viking yeah when I first read this I thought I would  be disappointed with just  an other HT cancer treatment but t seem the modified Thapsia garganica dos  fights cancer

This next bit  from the link you posted

Thapsigargin typically works by passing through cell membranes and shutting down calcium pumps – essential for cell survival – on the inside of cells. Denmeade's team modified the thapsigargin molecule by adding an extra peptide chain which prevents the toxin from entering cells. That is, until it encounters PSMA – an enzyme commonly found on the surface of many prostate cancer cells. PSMA cleaves the extra chain off the toxin, setting it free to do its devastating business.

The challenge lies in harnessing the power of this toxic substance, goading it into killing just the cancer cells while leaving healthy cells alone.

if researcher can do this it really will be wonderful but most times these drugs have some bad side effect but just hope this is not the case good post thank you for posting

Ray  

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