Thanks so much for your time bushy, I used the cream for 4 days and the same happened to me and it was not good, swelling and redness, so decided that I am not going to put myself through the misery. I may decide to do it at a later date. I am still miserable from the Efudix treatment on my chest and arms and the pain and itching are unbearable so can't imagine myself doing it to my face. Thankyou again for your help. Hope you wife doesn't have to go through it again.
Jo