Glioblastoma

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Hiii all..

my uncle has been diagnosed with glioblastoma( grade 4) this year in the month of Jan. the lesion was in the right parietal region.He underwent surgery. He has also completed radiation along with 5 cycles of temodal. But now, the tumour has reoccured. Is there anyone who has suffered through the same problem and has conquered. please let me know about the treatment who have opted. Does avastin help????

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rickglio

Sorry to hear about your uncle, I have entered my 14 month with my latest MRI 8/7/2012 looking good. I initially had surgery on 7/17/2011 followed by 30 days of radiation while taking temodar. I have been taking temodar 5 days a month along with avastin every two weeks for close to a year. Were all different, these therapies have worked for me and i believe avastin was a big help.

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siblingof
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Hi Pratts. Sorry to hear about your uncle. Avastin works in about 40% of glioblastoma patients. Avastin attacks VEGF, which is what the tumor uses to form blood vessels (angiogenesis). I don't know why it only works in some patients; it may be that not all tumors express VEGF?

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huxley2006