Women who don't have BRCA mutations could have other high-risk genes that affect treatment choices
by slbbw on Thu Oct 11, 2012 01:17 AM
So I know this does not affect too many here, but I thought I would ask anyway. Does anyone have experience with male fertility after temodar. I know there is a waiting period of somewhere between 6 months and 3 years for there to be no teratogenic effects, but that is a long window and we have not recieved a specific answer yet.
Has anyone here sucessfully conceived after Temodar. How long did you wait before trying to conceive. We certianly have a bit of time as my husband is just now coming off of the Temodar, or will be shortly. It would be nice to know what others have been told as to how long to wait.
by jon4156 on Sun Oct 14, 2012 12:34 AM
There doesn't seem to be alot of information about male infertility from Temodar available. I suspect this is because most males are probably beyond the family-building conception years when they are diagnosed and not interested in starting a family after diagnosis.
If you google search "male fertility temodar" you'll find statements that temodar affects fertility, but officially that information is based upon tests performed on rats and dogs at higher levels of temodar than those normally given to humans.
I know this doesn't answer the question you posed but it is all I could find.
by slbbw on Sun Oct 14, 2012 03:19 AM
Thanks for the attempt. There really is a dirth of information out there. So for teh sake of others I will answer my own question in case someone else finds this one day. We are officialy now done with the Temodar and the NO gave us some actual specific advice, besides the 6-12 months. We have been told for him to see a urologist when we are starting to think about it and they are suppose to be able to check sperm quality. This is still some hand waving but it sounds like there may be something to look for at least.
by rainflame4 on Mon Dec 17, 2012 12:03 AM
Thank you! I'm researching the same thing now so someone did find this one day. :)
by Bulley1 on Tue Dec 18, 2012 02:44 AM
Remembering Jenny from Idaho had a baby after her husband's diagnosis. Would have been 5-6 years ago. I take my hat off to you for considering adding to your family. It's easy to forget life goes on. The BT diagnosis is so overwhelming............................
by slbbw on Thu Dec 20, 2012 08:35 PM
It is an interesting time for this to come back up. We just had a scare about a possible pregnancy and the full 6 month window had not passed yet. I looked intyo everything I possible could and there is actually no link between infertility and birthdefects with Temodar that has been reported in recent literature. Our NO basically told us the same thing, but said to be on teh safe side give your body about 6 months to clear the drug.
We still plan on waiting a few more months, as that is what works for us, but there is little risk from what I can tell. the one study I did find was a case study of 6 women who became pregnant during treatment with temodar. They discontinued treatment and all went on to have healty uneventful pregnancies. While not a huge sample size, it is definitely reassuring for anyone considering this.
Of course we still haven't decided 100% simply due the chance of recurrence and having even more chaos to deal with if that were to happen. Hope this information can help anyone. I can find that paper again if someone is interested.
by hegartsh on Mon Jun 23, 2014 03:15 PM
I also have the same question. I lost a baby when my husband was diagnosed with a BT and still want to have a third. This was a year ago January and he just finished his Temodar this past February and we are wondering if its ok to try to conceive. I also worry about adding to the chaos should there be a recurrance as well as whether it will be able to happen because of fertility isuues in him. Very hard decision to make.
by Lorre_G on Tue Jun 24, 2014 04:12 PM
I have a couple of patients (men and women) who have gone on to successfully conceive. Two of the men each have 2 children and two of the women have two children. It does happen. I'm not sure how long they waited, however.
by blueskies12 on Wed Jun 25, 2014 10:18 AM
by hegartsh on Thu Jun 26, 2014 02:09 PM
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