ive used the search engine here and there are a few topics on this subject but nothing really tells what to do about the pain. my son went thru a second round of radiation (15 treatments) with temodar and avastin when the cancer cells spread to his csf. he was on a really high dose of dex, 24 mgs a day for 2 weeks and is being weaned down now but hes still on 14 mgs a day for this week. theyre trying to get him back down to 4 mgs a day. im guessin the knee pain is from the dex but has anyone found anything other than hydrocodone to help? he says it hits him about 4 am every morning and it affects his walking pretty bad. when i see him walk i can almost hear him grimace at every step. when this first hit about a month and half ago he lost the ability to walk and was in a wheelchair but as soon as treatment started within a week he was walking again, not sure if the high dose of steroids masked the problem or the treatment actually did the trick but he says this is a different kind of beast. he felt no pain when he was in a wheelchair he says his legs just quit working