Maintenance chemo - (erbitux) - questions

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Maintenance chemo - (erbitux) - questions

by Shitulpatel on Thu Nov 01, 2012 08:52 AM

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I had resection of sigmoid colon in July 2012 and liver resection in august 2012. RFA to mets in august 2012. Pathology report of colon tumour shows pT2 N0 Mx, liver mets pathology was mostly necrosis from the chemo. This was after 10 cycles of FOLFOX plus erbitux biweekly and erbitux weekly. Adjuvant chemo started mid Oct 2012. Done the 11 th cycle of FOLFOX plus erbitux . The 12th cycle starts tomorrow. Oncologist has recommended a maintenance chemo of weekly erbitux for 3 months after completion of the 12 cycles of FOLFOX and erbitux. I am reluctant to do this maintenance chemo due to QOL issues and side effects of rash and dryness due to erbitux. Any advise , suggestions on this recommendation of maintenance chemo from my oncologist ? I will have the Ct-pet scan sometime mid November 2012. This will the first proper scan CT and PET after the surgery. I would welcome any help and suggestions to the maintenance chemo being recommended as I feel weekly erbitux for such a long period may not be warranted in this case. If anyone has experience or access to any other opinion from their oncologist I would appreciate the information. Thanks Sdp

RE: Maintenance chemo - (erbitux) - questions

by Roswell on Sat Nov 03, 2012 10:19 AM

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On Nov 01, 2012 8:52 AM Shitulpatel wrote:

I had resection of sigmoid colon in July 2012 and liver resection in august 2012. RFA to mets in august 2012. Pathology report of colon tumour shows pT2 N0 Mx, liver mets pathology was mostly necrosis from the chemo. This was after 10 cycles of FOLFOX plus erbitux biweekly and erbitux weekly. Adjuvant chemo started mid Oct 2012. Done the 11 th cycle of FOLFOX plus erbitux . The 12th cycle starts tomorrow. Oncologist has recommended a maintenance chemo of weekly erbitux for 3 months after completion of the 12 cycles of FOLFOX and erbitux. I am reluctant to do this maintenance chemo due to QOL issues and side effects of rash and dryness due to erbitux. Any advise , suggestions on this recommendation of maintenance chemo from my oncologist ? I will have the Ct-pet scan sometime mid November 2012. This will the first proper scan CT and PET after the surgery. I would welcome any help and suggestions to the maintenance chemo being recommended as I feel weekly erbitux for such a long period may not be warranted in this case. If anyone has experience or access to any other opinion from their oncologist I would appreciate the information. Thanks Sdp

I have colon cancer that spread to the liver and then to the abdominal area. They gave me 6 months. Went on erbitux for an entire year and the tumors were all gone. The rash and fatigue were the worst part. My oncologist said the cancer would come back. I went on maintenance chemo last September and the tumors were back in the liver by March. Went on another treatment I was on a few years ago which became ineffective last month. I am starting another treatment this week. Have been doing this off and on for 10+ years but have been through all the available drugs. Erbitux was the most effective treatment for me. Best wishes.

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