Zelboraf stopped working

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Zelboraf stopped working

by lsv12 on Thu Dec 27, 2012 02:24 PM

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My husband just finished a clinical trail for Zelboraf and a MEK drug at Moffitt cancer center in Tampa, FL.  He was on the trial since Jan. 2012.It stopped working after 10 months.  He had spots on his rt tibia,right salivary gland, 1 on left bicep where it all started,3 on his lungs, 1 on kidney, liver and one in abdomen cavity.  They all decreased in size by 38%.  Only side affect he had was more fatique than normal. But he was not taking the Zelboraf alone.

He just had scans last week and everything has out of the blue has doubled in size.

He was taken out of the study and we will now go into another study that starts in January. It is for Yervoy and another drug together.

This unfornately is the last drug of choice to try.  We are once again moving forward towards the unknown.  I know it is all in GODs hands,  We live everyday to the fullest and appreciate each on a daily basis even more.  

Will keep posting where we are in treatment,

RE: Zelboraf stopped working

by Sweetpea4ever on Thu Jan 03, 2013 07:53 PM

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I am so sorry to hear about your husband ..my prayers are with you and your family. I am dealing with nightmare and husband finishing treatment for brain mets. He was pos for BRAF and we are in limbo until CT scan tomorrow tells us how fast it is growing. Is the Zelboraf for BRAF? I am looking for info always....and fear the moment when we reach the last med available. Please provide any info u have that might be helpful. I look to those who have journeyed before us, with us, and after us! God bless Monica

RE: Zelboraf stopped working

by lsv12 on Wed Jan 16, 2013 02:19 AM

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We are currently awaiting eligibility for another clinical trail at moffitt in Tampa.  It is Yervoy and another drug together. The Zelboraf is for BRAF.  I will keep you posted.

RE: Zelboraf stopped working

by Sweetpea4ever on Thu Jan 17, 2013 03:42 AM

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Hi. Just wanted to check in. I am having such a tough night. My husband had a suregery for the mass in his belly and just got home yesterday...He is miserable tho and mainly due to mood. We have not even started the Yervoy! He has NO appetite and has lost about 20+ lbs and is really struggling with t his. Any suggestions? I have seen so many rec for txments that are supposed to help with cancer...but he is not wanting to do them. I am desperate and he is so depressed. I cannot sit back and watch my husband give up like this.

Please offer any info that you have. Talking to his family is too diff as they cannot handle anything right now.

Thank you in advance!

Monica

RE: Zelboraf stopped working

by wlins on Fri Jan 18, 2013 07:32 PM

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On Dec 27, 2012 2:24 PM lsv12 wrote:

My husband just finished a clinical trail for Zelboraf and a MEK drug at Moffitt cancer center in Tampa, FL.  He was on the trial since Jan. 2012.It "" target="_blank" rel="nofollow">http://2012.It " target="_blank" rel="nofollow">2012.It stopped working after 10 months.  He had spots on his rt tibia,right salivary gland, 1 on left bicep where it all started,3 on his lungs, 1 on kidney, liver and one in abdomen cavity.  They all decreased in size by 38%.  Only side affect he had was more fatique than normal. But he was not taking the Zelboraf alone.

He just had scans last week and everything has out of the blue has doubled in size.

He was taken out of the study and we will now go into another study that starts in January. It is for Yervoy and another drug together.

This unfornately is the last drug of choice to try.  We are once again moving forward towards the unknown.  I know it is all in GODs hands,  We live everyday to the fullest and appreciate each on a daily basis even more.  

Will keep posting where we are in treatment,

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There are so many approaches to killing cancer using natural substances, that I cannot list them all here. Please do not suffer. Metastatis is often caused through conventional treatments, even at early stages. If you choose to continue with conventional therapies, at least try to add the natural approaches. The body must have the nutrients it is made out of to survive, just like a plant. Conventional methods and drugs further deplete the body's immune system to do it's job. The immune system is the organ that must be strengthened through nutrition in order for that organ to do the job it was designed to do, and that is protect the body from disease. If the immune system is compromised, that is why we get diseases. The diet must be rich in nutrients. Do not eat alot of acidic foods. Stay away from sugar. Let the natural plant sugars do their job to nourish your brain and body.

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