Recurrence & methylated

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bernadettep bernadettep
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Recurrence & methylated

by bernadettep on Mon Jan 21, 2013 04:10 AM

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Hi A couple of weeks ago at our appointment with NO she mentioned 'the good news is the tumour is methylated" My husbands original tumour was right frontal lobe and after 15 months of tmz, while on chemo, he had a recurrence in left frontal lobe . Currently on Avastin. At this point does methylation status even matter? Thanks for ant comments. Bernadette

RE: Recurrence & methylated

by lucyat24 on Mon Jan 21, 2013 06:18 PM

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My husband is also methylated.  He did very well on tmz, almost exactly 2 years and just had a recurrence.  He too, is on Avastin now.  I don't believe methylation matters with Avastin.  I haven't seen any studies.

RE: Recurrence & methylated

by RobinMB on Tue Jan 22, 2013 01:10 AM

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I think being methylated is a good indicator that you will respond to Temodar and you may have a longer life expectancy.  :)

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