My husband has advanced colon cancer with metastesis to the liver. He has tried three types of chemo. The first one slowed the process way down, but then it started to grow a bit. Switched to another chemo. CEA went up. Switched to the last chemo, liver enzymes skyrocketed. Does anyone have experience with doing all this chemo and returning to the first type of chemo? I understand the cancer is resistent, but wondered if anybody had tried it?