filtering out tumor secreted exosomes to unmask cancer cells

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filtering out tumor secreted exosomes to unmask cancer cells

by vinaykumar on Thu Feb 21, 2013 04:29 PM

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came across this intresting technology which is/was suppoed to be tested in filtering out tumor secreted exosomes from the blood. these exosomes supposedly play a big role in desensitizing the immune system.

the filter (  Hemopurifier ) is being used in india for HCV and pending approval from FDA

does anyone has more info on this?


In vitro studies have also documented that the Hemopurifier® captures exosomes underlying cancer, including colorectal, lymphoma, melanoma, ovarian, and breast cancer.  We have expanded our exosome research programs through a collaborative agreement with the Sarcoma Oncology Center (SOC), based in Santa Monica, California. The SOC collaboration is studying the ex vivo effectiveness of the Aethlon Hemopurifier® to remove immunosuppressive exosomes from the blood of advanced-stage cancer patients.  The study will evaluate 25 patients, five patients with metastatic cancer of the following types; non-small cell lung cancer, prostate cancer, melanoma, head and neck cancer, and sarcoma.  Exosomes released by cancers have emerged to become an important therapeutic target in cancer care, as they are implicated in cancer survival, growth, and metastasis.  Researchers have also identified that cancer-released exosomes assist tumors in evading the response of the immune system.

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