We did postpone treatment due to my husbands moms passing. Thanksgiving day was the 21st day to go without treatment. He started to hurt that day. So now it seems that his pain could be from postponing the treatment. He so needed the break. I don't know that I would recommend this to anyone. Just know what the outcome could be. Even the Dr. is not sure the extreme pain is from going without chemo but could be.He said he was actually ready to get back on the chemo.