I took my Maltese cross shitzu to the vet for excess urination and after 3 visits she had a ultrasound and will know tomorrow but she has a tumor in her trigonal area the size of a cherry tomato she is only a small dog 4kilos so I suppose thats large. I found a site that is on the internet that has herbal treatments pre-made one is called bladder cancer support herbal treatment and you can order it on the internet (from Australia) has anyone ever tried this Robert McDowell's they answer emails very quick I'll say that for them and seem very helpful.....my dog is as fit as a fiddle and still would like to chase the odd roo across the paddock if you let her out of the car (which I don't) but because she is so fit and has been the perfect dog, not a problem in 11 years, people said in the vet she looked like a young dog I need all the help and info I can get to help her out and pay her back for everything she has done for us over the years. This site took me 3 days of 5 hours a day to find because initially I thought it was only for humans......it has come at just the right time I was at the end of my tether and thought I had no more tears left, all vets should have this site and give it to all owners, my heart goes out to all of you