I was on Xeloda and it did seem to retard the growth of my cholangiocarcinoma. Unfortunately I developed periferal neuropathy when my dose was increased to 4000/mg/day, so my oncologist dropped me back to 2000 and then up to 3000, where the symptoms began again. Another drop to 2000 was okay for a while, but soon the PN showed up again. When I was at 4000/day, the pain was quite intense. It never got that bad again at the lower doses, but it was still painful. My doctor put me on Lyrica, which I believed helped. Neurontin and Elevil are also used to treat PN. Now I'm on taxotere and camptosar, which of their own side effects, but not nearly so painful.