Has anyone else experienced mental "fog" & extreme fatigue while taking Iressa? My mother was moved up to a double dose & shortly after starting that became incoherent, unsteady on her feet & slept all the time. She had no visible side effects when she was on the regular dose but they moved her up to a double dose to try to shrink the tumors (reg. dose had stopped their growth). The case manager, after hearing of the extreme change, told her to stop taking the meds & get to the doctor or hospital for an eval. They (the ER-she was taken there by the squad after a fall in the shower) couldn't find any cause other than the Iressa. This doesn't seem to be a "known" effect. Now it is.