Hi, My husband has been out of treatment from July 2003. He had massive treatment for nasopharyngeal stage 4 advanced. He now has severe fibrosis resulting in spreading to the upper chest vascular system. His treatment was front, back, both sides. The more being on the right, which is where fibrosis started, but is spreading. He already takes the Trental with vit. E. I've looked into the Pirfenidone trial with no luck. He gets frequent flare up things with fever swelling etc. He has been on multiple antibiotics, and prednisone. Does not last more than one month for relief. Any suggestions may help. I am in frequent contact with his doctors, and they will try anything they can within protocol. Thanks for any advice. B Johnston