When my wife was first treated for her ovarian cancer back in 1972, she presented with DVT and pulmonary embolism associated with her malignancy. Persistent effusion showed malignant cells on thoracentesis. This is an indication of stage IV cancer. She had a total abdominal hysterectomy and pill-dose Chlorambucil (Leukeren) treatment. She had talc placed into the lung walls for them to adhere to the lining and keep them from collapsing.
Twenty-four years later, she developed a metastatic transdiaphragmatic tumor from the original cancer with attachment to the lung and other midline structures of the chest. Parts of those structures were surgically resected. I remember the throacic surgical oncologist telling me the talc oozed down to the bottom of the cavity and was as hard as rock. She had to literally use a hammer and chisle to clean it all out.
It seems that her twenty-four year ride without any recurrence gives the University of Florida study on Talc some credence. Would she have gone twenty-four years without this talc? The fact that she took Premarin for over twenty years was probably the best indication why she ever got a recurrence.