My husband was just diagnosised with myelofibrosis, and is still feeling fine at this time is not getting any treatments, but his liver and spleen are both enlarged, and is feeling some discomfort from the enlarged spleen the doctor said he has maybe had this condition for a few years. two years ago we started with protein in the urine wonder if others have had this problem. he is still able to work he is 61 years old. there is a new drug that they might try called lenalidomide, when it come to the point he needs something. wonder why we have to wait until this gets bad., before medication is given. I am having a really hard time dealing with this. pete