I broke my clavicle back in March and discovered it was due to a plasmacytoma. Additional test were done and I was diagnosed with MM. I did not have any other symptoms associated with this disease. A bone survey showed that there were small lytic lesions in my long bones and most likely represented MM. A bone marrow aspirate showed 4% monoclonal plasma cells using flow cytometric.A special stain showed individual and cluster of kappa clonal plasma cells overall accounting for15-20% of total nucleated cells. My blood work showed the following:
IGA 66 mg/dl
IGG 1325 mg/dl
IGG 36 mg/dl
Protein 7.6 g/dl
Albumin 4.3 g/dl
My M-spike at that time was 0.7 g/dl and it was IGG. I went on Thalomid and Dexamethasome. During May through September my M-spike went to 0.4, 0.2 and to where it could not be measured. Because of the side effects of the medication, I took myself off because I wanted to see what would happen next with my M-spike. My Doctor, however, suggested that I have a stem cell transplant.
My question is with a very low M-spike and a normal range for IGG, what should my next step be ? My wife wants be to get a second opinion which is fine but I do not want to stay on medication the rest of my life. I even question if I should be treated right now or just monitor the situation.
Any input or advice from someone with more experience with MM would be appreciated.