My 23 yr old daughter is being tested for Leukemia, she had an slightly high WBC of 11.7 for over a year..... she does smoke maybe 1 cigarette a day, and sometimes will go 2 to 3 days without smoking. She was having some joint pain in her feet, which was contributed to gout, because she had a high Euric Acid level.
She had a BMB done, and we just got the test results back, but still need to see the doctor.
Can anyone dealing with CML, make anymore sense of the tests results, while we wait in the mean time.
It looks like they did not get enough biopsy for a clear diagnosis....
1). Suboptimal Specimen with Cellular Bone Marrow
2). Slightly left shifted Granulopoiesis
3). Absent Storage Iron with no ringed sideroblasts
4). Moderate Increas in Reticulin Fibers
FISH anaylsis shows no BCR/ABl translocation (AGT07-8093). Although there is no apparent evidence of CML, chronic myeloproliferative disorder can not be completely excluded. Cytogentics studies may be helpful by finding re-occuring cytogentic changes typically associated with CML. Re-biopsy is recommened if indicated. Correlation with clinical and other diagnostic information is recommended.
WBC 11.7 ; Neutrophils 71 % ; Hemoglobin 13 ; Hematorcit 39.4 %; Lymphocytes 27%; Monocytes 1 %; Eosinophils 1 %
Bone Marrow Differential Count: Number of Cells counted: 300
Myeloid Cells 76% ; Erythroid Precursor Cells 3 % ; lymphocytes 19%; Monocytic Cells 1%; Blasts 1 %
The C-Kit also stated: Stained rare scattered myeloid precursor cells.
What does all this mean??
Any input is greatly appreciated.
Thank you
Lisa