I would like to know if anyone knows what the free kappa serum value has to be for a m-spike to show up in a protein electrophoresis test. My original m-spike was 0.7 in late April.. I was on thalomid and dexamethasone until mid-Sept when the m-spike could no longer be measured. I went off the medicine and since mid-Oct. my free Kappa serum has went from 42 mg/l to 85.7 mg/l. My free kappa/lambda raio has went from 5.0 to 8.8. I am not sure how serious this is and should I now consider a transplant. My Doctor is pushing the transplant option.