On 1/17/2008
rharri10 wrote:
I would like to know if anyone knows what the free kappa serum value has to be for a m-spike to show up in a protein electrophoresis test. My original m-spike was 0.7 in late April.. I was on thalomid and dexamethasone until mid-Sept when the m-spike could no longer be measured. I went off the medicine and since mid-Oct. my free Kappa serum has went from 42 mg/l to 85.7 mg/l. My free kappa/lambda raio has went from 5.0 to 8.8. I am not sure how serious this is and should I now consider a transplant. My Doctor is pushing the transplant option.
Good Evening;
I am not familiar with "free kappa serum value". Kappa Free Light Chain (3.30-19.40) and Lambda Free Light Chain (5.71-26.30) but not the former.
K/L Free Ratio should fall between 0.26-1.65.
Have you had a bone marrow biopsy showing the cellularity of the plasma cells? A skeletal survey showing the appearance of your bones? And a CT scan showing any abnormalities of you skeleton? What stage are you presently Dx?
I'd get those other tests done before I was talked into a SCT. You may be able to treat your MM with the newer meds being offered or even a change in your diet prior to going through a transplant. Stay informed.
Take care;
Kevin