Don't give up. I too had a very rough go of it after 8 treatments with taxol and carbo. Try everything. I began to pay very close attention to nutrution. Organic chicken, fresh salmon lots of greens and fruit. Lots of green tea. I was so tired and it seemed if the leg and joint pain left me feeling old and exhausted. I started cooking in the morning as often as I could and made nutrition for myself and my son and husband my focus. I'm taking a vitamin drink that has done wonders. If you want the name email me. I was told I was just depressed but I don't beleive it. Go to a health food center and read about natural remedies. I went to physical therapy to help with leg pain. It helped. Don't let people tell you it is psycological. It isn't,