Hey Chevydude,
I will be starting my 12th cycle on Sutent 50 mg in two more weeks. The side effects I have seen have been somewhat unpredictable. I have experienced different side effects to varying degrees in each cycle. Naucea and general tiredness have been pretty common through most of them. I have had the foot and hand syndrom during some of the cycles some worse then others. I have found taking three 100 mg tablets of vitamin B-6 a day along with Udder Smooth or Udder Balm have really helped. I used the balm with my skin became raw (open sores). The longest time I experienced pain in my feet has been 3-4 days. I have had sore hands a number of times making it difficult to use my hands. On one occasion, my hands peeled with the skin on my fingers and palms coming off. I have had diareah during most of the cycles, however I have a colostomy bag so it was as painful as it could have been, just inconvenent. There were nose bleeds on occasion. I also had some severe back pain and difficulty breathing during another cycle. I havent experienced the sore mouth so far. My sister, who is an RN in the cancer field told me about the B-6. She also told me about a mixture we can use to ease the pain in your mouth. I can check my old postings to this board on how to make it if you are interested. She got this info from the Drs she works with who use it on their Sutent patients.
You might want to talk to your oncologist about getting a MUGA Scan to establish a baseline for your heart. Sutent has been known to cause problems with patient's heart It actually measures the effeciency of how your heart is functioning. Also check with you Dr about the vitamin B-6 just to make sure but it shouldnt be a problem. The largest tumor I have in my right adrenal gland has shrunk from 5 3/4 cm down to 1 1/2 cm. The others have pretty much disappeared. The shrinkage has stabilized now but the good news is that nothing is getting larger.
Good luck!