My husband is finishing cycle 10 this Sunday and for the past 4 cycles he has suffered on his time off. The second week is worse and he has pain in his back and sides. He sometimes has that much pain it causes him to lose his appetite and causes vomiting. His oncologist explains it as the cancer is in withdrawals from the sutent. It has to the metabolic make up of the drug and what it does to the tumors. It is a side effect. Hope this helps
Mary