I am not aware of the average heal time but I can tell you I was worried when I saw these blogs and the effects:
http://www.sannerud.com/people/efudex/index.html
and
http://myefudex.com/1.html
Again, I think the gentle scrubbing, vaseline from hours 4-12, and shaving made the difference.
Clearly, Celebrex made it worse and more irritated but I did see a whole new layer of lesions surface and die when I combined the 5FU and celecoxib.
Here is a photo of my forehead which was treated with Efudex for 21 days.
http://allyoucanupload.webshots.com/v/2003630338164441404
The small redspot in the middle is actually a spot caused most likely by the constantly oily surface. I'm 45 years old and still get pimples like a teenager! My mom got them into her 60s.