Hi ALL
Being stage 4, have been avidly resarching net. My background is CA125 pre Op 1800, post op 1047, after chemo 1 (taxol/carboplatin)=443, chemo 2 =111, chemo 3=60. Next chemo next Tues. Have learned lots. For what its worth my regime now is eating mostly raw veg/salads, less fruit because of sugar. Pound for pound red peppers contain more Vit C than an orange (canteloupe melon is alkaline). Lemon, once digested, is alkaline so having lots of warm fresh lemon water. Adhering to Acid/Alkaline regime, NO sugar, NO dairy, use unsweetened soya milk and love almonds (being alkaline) plus usual flax OIL (not seeds). Just read v promising info re ginger:
In laboratory studies, researchers found ginger caused ovarian cancer cells to die. Further, the way in which the cells died suggests ginger may avoid the problem common in ovarian cancer of cells becoming resistant to standard treatments.
The researchers are presenting their results in a poster session at the American Association for Cancer Research annual meeting.
Researchers used ginger powder, similar to what is sold at grocery stores, only a standardized research grade. The ginger powder was dissolved in solution and applied to ovarian cancer cell cultures. Ginger induced cell death in all the ovarian cancer cell lines tested.
Moreover, the researchers found that ginger caused two types of cell death. One type, known as apoptosis, results from cancer cells essentially committing suicide. The other type of cell death, called autophagy, results from cells digesting or attacking themselves.
"Most ovarian cancer patients develop recurrent disease that eventually becomes resistant to standard chemotherapy - which is associated with resistance to apoptosis. If ginger can cause autophagic cell death in addition to apoptosis, it may circumvent resistance to conventional chemotherapy," says study author J. Rebecca Liu, M.D., assistant professor of obstetrics and gynecology at the U-M Medical School and a member of the U-M Comprehensive Cancer Center.
Study results are very preliminary, and researchers plan to test whether they can obtain similar results in animal studies. The appeal of ginger as a potential treatment for ovarian cancer is that it would have virtually no side effects and would be easy to administer as a capsule.
Ginger is effective at controlling inflammation, and inflammation contributes to the development of ovarian cancer cells. By halting the inflammatory reaction, the researchers suspect, ginger also stops cancer cells from growing.
"In multiple ovarian cancer cell lines, we found that ginger induced cell death at a similar or better rate than the platinum-based chemotherapy drugs typically used to treat ovarian cancer," says Jennifer Rhode, M.D., a gynecologic oncology fellow at the U-M Medical School.
Liu's lab is also looking at the effects on ovarian cancer of resveratrol, a substance found in red wine, and curcumin, the active ingredient in the curry spice turmeric. In addition, researchers at the U-M Comprehensive Cancer Center are investigating ginger to control nausea from chemotherapy and ginger to prevent colon cancer. This article was published in April 06. Also found another article published Oct07. I wonder if it relates to the above ginger article. Just in case I have started muching on a bit of fesh grated ginger...its not bad! Herewith other article mentioned:
Hope for ovarian cancer vaccine |
Ovarian cancer often returns |
A vaccine for ovarian cancer has produced "encouraging" results in preliminary trials, US scientists say. The vaccine is designed to enhance the body's own immune response to the cancer, said the Roswell Park Cancer Institute, based in Buffalo, New York. Most patients with advanced disease respond to chemotherapy, but more than 70% die from a recurrence of the cancer within five years of diagnosis. Cancer Research UK welcomed the study but said further trials were needed. Details of the study appear in Proceedings of the National Academy of Sciences. | We are confident that the vaccine will eventually be widely available
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The vaccine contains an ovarian cancer protein fragment coupled with a molecule known to induce immune response. It targets a protein produced in a high proportion of ovarian cancer cells, but not in healthy cells. The researchers tested it in women with epithelial ovarian cancer, a cancer type that originates in the covering of the ovaries. They said although their study was designed as a phase one clinical trial - a preliminary study - it had produced "encouraging" results. Dual effect The vaccine induced the immune system to produce antibodies, and to mobilise specialised T cells which were able to target cancer cells producing the key protein. The researchers detected vaccine-induced immune cells in patients up to 12 months after immunisation, suggesting a long-lasting effect. Lead researcher Professor Kunle Odunsi said: "There is now compelling evidence that the immune system has the capacity to recognise and kill ovarian cancer cells. "Our vaccine strategy is simply taking advantage of this knowledge in an effort to improve the outcome for ovarian cancer patients. "We are confident that the vaccine will eventually be widely available." Dr Alison Ross, of the charity Cancer Research UK, said: "We welcome any research that could lead to improved survival for people with ovarian cancer, and cancer vaccines have exciting potential. "This early trial shows encouraging results but it's important to remember that much larger studies will be needed before we know for sure whether the vaccine is safe and effective." |
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