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Myelofibrosis--I Need Some Help Please

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JuJusdaughter
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Subject: RE: Myelofibrosis--I need some help please
Date: 03/14/2008

Hello... I hoped that I could help...

Your post touched my heart, and today I pray for  you and your mom.  I have no other help -- only questions and if you do not mind, might you or others help me understand a little more about myelofibrosis?

I tried to find info at the Mayo Clinic site.  I understand a little more, but what was not mentioned is

Hello... I hoped that I could help...

Your post touched my heart, and today I pray for  you and your mom.  I have no other help -- only questions and if you do not mind, might you or others help me understand a little more about myelofibrosis?

I tried to find info at the Mayo Clinic site.  I understand a little more, but what was not mentioned is how long a person can have this and how slow or how fast it progresses.  In the marrow, from one single morphed stem cell, scar tissue invades creating abnormal, sick, few and overpopulation of various cells... (in a nut shell?)  How long does this process take before complications become extreme? 

 I imagine that initial onset and early symptoms might be fatigue, aches and pains.... can anyone tell me how long this early stage usually lasts?  Does it vary? 

 

Thank-you for your time.  I love the love between my children and me.  How sweet you love for your mother.

 

In LOVE sincere

AnotherMother

 

 

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                                                                                                                                    Stages: this does vary from patient  to patient really. My mother's early symptoms were  lack of energy, unusual brusing (like someone had rubbed soot into her skin), noticable wieght loss in a very short time and leg pain. She may have been developing these problems for a while before she was diagnosed.

Her Cause: A chemotherapy medicine used to treat breast cancer in addition to radiation. This combo has been determined to cause this disease. But what are you gonna do? You take your chemo and radiation treatments and you kick cancers butt! That's what ya DO!

This doesn't mean this will happen to everyone! It's still a rare disease ok?  Other possibilities:  prologned exposure to benzene can cause this disorder too. Commercial detergents, bleach, gasoline, and you can even find it in the tobacco of our cigarettes. They put that poison on the leaves so the tobacco will not burn up to fast!   I  still haven't figured out how that is legal!

Your next quesitons:

How slow/how fast /how long: With my mothers situation she had bout six months before she required blood transfusions at that time she delt with leg pain, night sweats and bruising Now in her second year of mainating, she has one transfusion every 3 to 4 weeks, and recently had to add plateletts transfusion along with the red blood cell transfusion.  She now keeps her leg pain under control with vicoprofen. The nose bleeds have not been as bad lately, since she will never take asprin again.  Now, she also gets fever when her leg pain is bad. The nurse had to give her delauded during her last transfusion. She wasn't having a reaction or anything, thats just the disease flaring up when usualy no one is around when that happens. Her other symptoms that weren't there in the first six months were;loss of concentration,short term memory loss and confusion.

 She is stable right now, but you can see that the disease has progressed over 2 years. I say stable because her liver and spleen show no signs of enlargement, and her symptoms are these that I mentioned and there are no more to add to the list right now.

So this is the hardest part for caregivers...you never know when the disease will begin to transmutate. I hope this helps you in some way!

I am amazed at her innerstrength, even though she has pain that constantly reminds her of the inevitable. :(

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