I asked my husband's oncologist if PC ran in families because I was worried about the kids. He said that there is a familial form of PC, but it only accounts for about 10% of the cases. I don't know how they determine if you have that form, Surely, other family member with PC would be an indication. President Carter lost both parents, two sisters and his brother to PC- there's clearly a family connection there!. This is something you should ask your oncologist about. I would also ask if there are any clinical studies being done that your children could participate in that will hopefully help lead to better earlier detection.