So sorry you find yourself in this situation. Melanoma is so un-predictable. Although I agree with all that has been said, I wanted to mention that even if you decide to go with the trial, sometimes, you cannot qualify based on the blood work (tissue typing). My son decided against interferon and was accepted into a trial at NCI, only to find out the day before he was to begin, that the bood work came back with a factor that dis-qualified him. He has chosen to do only supplements for now to strengthen the immune system. He did not feel the interferon treatment was statistically promising enough to endure the year of treatment. I think it is fair to say that there are several trials that have shown much promise with good results as previous poster said. The interferon could delay recurrance but not improve overall survival according to statistics.
Only God knows, really, what each will respond to. Hope you can put it in His hands.
Good luck with this ever so hard decision.
Mrs. C