Well Kevin "tandem" Tandem could be different things in our case "tandem" means transplant of stem cells from himself and a sibling together His cancer is so vigorous that Yale believes it will return quickly therefore sibling stem cells could identify Myeloma and destroy it. The problem is that I am not a HLA match and we have only a sister who is being typed at this time. We are hopeful. The chance of HLA match is only 25%. The most amazing thing is at Yale. They have a super computer this computer has "linked" with my brother it was connected by a IV.his breathing was connected and his urine was collected It even used a special camera to watch his heart flow and many other functions.......after about 1/2 hour it learned all about him and it "knows" what it needed to CURE him. (we may not be able to supply it with what it asks for) but the computer collects& COUNTS every stem cell and what products are needed for transplant. Then when he is ready for transplant it will supply whatever he needs at an EXACT amount and if there is any stress it knows either to slow down or speed up or introduce medicine for whatever organ that may stray from "baseline" They have informed us that this type of computer exists only at Yale.. The Doctors are among the best in the world so we have to put our trust in a computer and these fine doctors.This procedure is to happen later in march. he will undergo the typical chemo to stimulate production of stem cells and then once completed he will receive by computer the high dose chemo and will "know" when the maximum amount of myeloma cells are killed. Without a sibling match the cancer will return sooner but his superlative response to Velcade/thal/dex.could be used again when he comes out of remission. also revlimid and other drugs are still available to him. Cancer sucks.!!