My husband was diagnosed at age 60 with prostate cancer. The gleason was 8 and the psa was 147. The surgery was delayed six months from the PSA reading of 147. He had 3 months of ADT before the surgery and the surgeon was very happy with the outcome of surgery - negative margins and negative venus, lymph node, and seminal vesical involvement. However there was single foci extraprostatic extension and perineural invasion on one side. The PSA 3 months post RP was <.1 - again happy news. However at 6 months Post RP the PSA was up to 4.7 and 3 weeks later was at 7.5. My husband received his first dose of Lupron in mid October 07 and another the end of February. My question is, is there anyone out there that can give me some information on what to expect in the future? I am assuming I will be retiring alone in 5 years because of my reading on the subject. Sure would be helpful to "speak" with other women who have been in this position (must be lots of them). I cannot talk to my husband because he is in denial and if this works to make his life happier I don't want to burst that bubble.