Sorry to hear about your husband. I was diagnosed with CML last year and am still learning. I believe the bone marrow biopsy will give the doctor a better look at what is going on. I had one done so they could see what type of leukemia I have. I have to get on done once a year and am not looking forward to it. Tell your doctor to give your husband something to calm his nerves and for pain during the procedure. It is not a pleasant one.