I find that after about three and a half weeks I can no longer tolerate the sutent and most of the time stop taking it because I get so sick i can't stand it. I have wanted my doctor to lower the dosage so I can tolerate it but so far he hasn't and I don't understand why. If I can't take it then a lower dosage makes sense to me. It is frustrating to me. It makes me so sick and my skin turns yellow and of course you can't taste and you get a salt sensitivity and can't eat hot things. I get horrible diarhhea and am so weak. I am stable and am so far doing all right. I just hate the way that drug makes me feel and I hate that for weeks on end I am sick as hell and don't enjoy my life at all. I just don't want to take it anymore. And the cost of this drug is almost $7000 a month. Even if you are rich who can afford that? I wish I were like some of you that have little side affects because to me it feels like I have acid in my stomach the likes of which I have never experienced before.