I have been on Tarceva now for two and a half months after four months of IV chemo, which began to fail towards the end. I feel very positive effects of my lung power and breathing and being able to walk a long distance , much of it uphill, in the early mornings. My skin 'rash' and dryness is a daily problem and I appreciate reading other peoples solutions to hydrating and treating the skin. I also cannot bear to be out in the sun as I get terribly prickly all over. I have times of anxiety and stress which seems like drug reaction...My hands feel numbish and I feel 'out of control' and unable to focus my energy. Do other people feel this with Tarceva or is it related to the lung cancer and previous chemotherapies?? I wonder if anyone experiences a time frame during the 24 hours between Tarceva pills where they have more body stress and exhaustion.I have been taking Ativan ever since I began chemotheraphy and this seems to get me functioning through the day in 4-5 hour segments. I'm very interested to hear other peoples experiences,especially related to anxiety,memory and body reactions ,as well as hearing from people who have been doing well for a long time on this medication .Its very exciting to me to find this message board with people who are facing the same challenges..Thanks for all comments!