I have had symptoms of POEMS for several years and no doctor has every been able to figure out what was wrong with me. Finally after a month and a half my new neurologist diagnosed me with POEMS. I do have all 5 of the categories. I was concerned about this being passed on to my children. She said this is not hereditary. I am going to see a neurosurgeon on Thursday to see about a lesion that is in going into my spinal cord. Has stem cell transplants been successful for anyone? Is mayo the only place doing research on POEMS? Is anyone have a research studies on it?