Hi Kerrie,
I have been using Efudex all over my face for 16 days now and the reaction is awful. My whole face is very red but it looks like the actinic keratosis spots are the worst. Those spots (there are lots of them) are now scabbing and crusting over. It is painful now but my doc prescribed a cortisone cream called Desonide and I think it helps. You can apply this two hours after you apply the Efudex. I'm also using Eucerin Aquaphor. Neither of these products burn my skin when I use them. Also, I've been using Ibuprofen for the pain.
Hang in there and keep your eye on the prize. This too shall pass.
Good luck,
Cynthia