I wish we would have looked into this route of treatment. The Nexavar, Gamma Knife, Radiation, and Torisel all led to one solid year of no quality to my husbands life and a lost battle in the end. What would he have had to lose? I strongly recommend this to be considered by all Stage IV Renal Cell Patients who hope to have a bit of quality to their lives. Ahhhhhhhhhhhh, hindsight!